General Cell Lines and Cell Cultures
ATCC Escherichia coli
This whole-genome sequenced strain of Escherichia coli can be used in susceptibility testing and pharmaceutical testing. This strain is known to produce cephalosporins and 6-aminopenicillanic acid.
Medchemexpress LLC CD47 Human HEK293 5ug
CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1 affecting signal transduction cardiovascular homeostasis inflammation apoptosis angiogenesis self-renewal and Immunomodulatory It regulates pulmonary endothelin EDN1 signaling acts as a pressor in blood pressure regulation and is critical for memory formation CD47 Protein Human (HEK293) is the recombinant human-derived CD47 protein expressed by HEK293 with tag free
ATCC Staphylococcus aureus; 6 x 0.3mL
ATCC 29213-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 29213™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
Biochain Institute Inc Paraffin Tissue Section - Multiple Sclerosis Disease: Brain, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC T HESCs; Endometrium; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
Eurofins Discoverx PathHunter CHO-K1 CCR1 β-Arrestin Cell Line, 2 vials. (93-0254C2)
The PathHunter CCR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL3) based activation of CCR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR1 and EA-tagged β-Arrestin-2. Activation of CCR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Klebsiella pneumoniae; subsp. pneumoniae
Klebsiella pneumoniae subsp. pneumoniae strain [CIP 104216, NCIB 10341] was isolated from cow's milk. This whole-genome sequenced bacterial strain can be used in inhibition testing, disinfectant testing, quality control, and respiratory disease research.
Eurofins Discoverx cAMP Hunter U2OS HTR7B Gs Cell Line, 2 vials. (95-0156C3)
The cAMP Hunter HTR7B Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin/5-HT) based activation of HTR7B GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HTR7B, a naturally Gs coupled GPCR. Upon activation of HTR7B, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
iQ Biosciences Cynomolgus Monkey Bone Marrow Cells, 1M cells/vial
High-quality, high-viability (typically > 70%) cynomolgus (cyno) monkey (or macaque) bone marrow cells sourced responsibly from a vetted third party facility. Used for a wide variety of safety assessment and functional assays. All orders come with an iQ Certificate of Analysis.The following donor requests can be accommodated if inventory is available: - Single or multiple donors for a particular product (SKU). Indicate number of vials from each individual donor - Donor-matched PBMCs
ABclonal Technology MEK1 Rabbit pAb
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Eurofins Discoverx PathHunter CHO-K1 CHRM5 β-Arrestin Cell Line, 2 vials. (93-0519C2)
The PathHunter CHRM5 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. oxotremorine) based activation of CHRM5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CHRM5 and EA-tagged β-Arrestin-2. Activation of CHRM5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Lonza Walkersville Mouse C57BL/6 Hepatocytes, Cryopreserved, Plateable
Cryopreserved C57BL/6 Mouse Hepatocytes, Plateable are specifically pre tested for metabolic activity of general Phase I and Phase II metabolism in suspension.They are tested for healthy morphology lasting 72 hours in monlayer sandwich culture.Applications:Drug metabolism in plated monolayer formatSpecies-species comparisonsGenomicsContent:1 x Cryopreserved ampule of C57BL/6 Mouse Hepatocytes (plateable format) containing > 5 million viable cells
Abcam Tandospirone hydrochloride (Metanopirone), 5-HT1A partial agonist, 50MG
MW 419.9 Da, Purity >99%. Potent, selective 5-HT1A partial agonist (Ki = 27 nM). Decreases the firing rate of 5-HT neurons of the dorsal raphe. Shows anxiolytic and antidepressant effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter U2OS mFCGR2B Clustering Cell Line, 2 vials. (93-1139C3)
The Path Hunter mFcyRIIb clustering cell line is a stable, engineered cell line designed to increase signal produced from a Checkpoint Cell Line via antibody-mediated crosslinking of the receptors. This product is a companion product used to determine cross-linking based increases in potency of agonist antibodies. The cell line included overexpresses mFcyRIIb Fcg receptor. When co-cultured with a Checkpoint Cell Line in the presence of agonist antibody, the Fcg receptor binds to the antibody, inducing receptor clustering. The induced receptor clustering leads to increased activation and downstream signaling, leading to increased EFC signal production. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/checkpoint.
iQ Biosciences Human Irradiated PBMCs, 100M cells/vial
High-quality, high-viability (> 80%) irradiated peripheral blood mononuclear cells (PBMCs) from healthy blood donors sourced from a world-renowned blood center. Used for a wide variety of immunology-based applications, including in-vitro immunoassays and ex-vivo applications. All orders come with an iQ Certificate of Analysis.The following donor requests can be accommodated if inventory is available: - Single or multiple donors for a particular product (SKU). Indicate the number of vials from each individual donor - Positive or negative for EBV or CMV (for healthy donors only) - Good responder or non-responder to tetanus antibody (for healthy donors only) - HLA types for Class I and Class II alleles (for healthy donors only) - Donor(s) with a higher percentage of the cells of interest (e.g., B cells, CD4+ cells, CD8+ cells, NK cells, etc.) - Gender, age, body mass index (BMI), or ethnicity